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Twelve 28

Berberine+

Berberine+

Regular price $62.00 USD
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Berberine+

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About this product

Berberine+ Supplement

Add Berberine+ to your daily supplement routine with a carefully formulated blend of dihydroberberine, alpha lipoic acid, GBB (gamma-butyrobetaine), and cinnamon bark extract. This convenient berberine supplement is provided in an easy-to-use capsule format for individuals looking to incorporate a structured supplement into their everyday routine.

Berberine+ contains a combination of ingredients commonly found in modern wellness and nutrition formulas, including a berberine-derived ingredient and botanical extract. With 60 capsules per bottle and a simple twice-daily serving, it fits easily into established daily habits.

Key Features

  • 60 capsules per bottle

  • Convenient capsule format

  • Simple twice-daily serving

  • Contains dihydroberberine, alpha lipoic acid, GBB, and cinnamon bark extract

  • Designed to complement everyday supplement routines

  • Suitable for nutrition-conscious and active lifestyles

  • Easy to incorporate into a consistent daily routine

Berberine+ Formula

Dihydroberberine
A berberine-derived ingredient included as part of the Berberine+ formula.

Alpha Lipoic Acid (ALA)
An ingredient commonly included in nutritional and wellness supplement formulations.

GBB (Gamma-Butyrobetaine)
A compound included in the formula alongside the other selected ingredients.

Cinnamon Bark Extract 10:1
A concentrated botanical extract included as part of the Berberine+ ingredient blend.

Daily Supplement Routine

Berberine+ provides a straightforward way to include a multi-ingredient formula in a regular supplement routine. The capsule format makes the product convenient for everyday use at home, at work, or alongside an active lifestyle.

For those researching berberine supplements, berberine capsules, berberine plus supplements, or natural berberine supplements, Berberine+ combines a berberine-derived ingredient with additional selected ingredients in one convenient formula.

Suggested Use

Take one (1) capsule twice daily with food, or use as directed by your healthcare professional or product label.

What's Inside

  • Dihydroberberine

  • Alpha Lipoic Acid

  • GBB (Gamma-Butyrobetaine)

  • Cinnamon Bark Extract 10:1

Who May Include Berberine+ in Their Routine?

Berberine+ is designed for adults looking to incorporate a multi-ingredient supplement into their regular routine, including people interested in:

  • Daily supplement routines

  • Active lifestyles

  • Nutrition-conscious living

  • Berberine supplements

  • Berberine capsules

  • Berberine-based nutritional formulas

  • Structured everyday wellness routines

About Berberine Supplements

Berberine is a naturally occurring compound that is widely discussed in nutritional and wellness research. People researching berberine for weight loss, berberine for blood sugar, berberine for cholesterol, berberine for insulin sensitivity, and berberine for metabolic health will find a wide range of educational information about the ingredient.

Berberine+ is presented as a dietary supplement containing dihydroberberine alongside alpha lipoic acid, GBB, and cinnamon bark extract. It is not intended to replace a varied diet or healthy lifestyle.

Product Details

Product: Berberine+
Format: Capsules
Count: 60 capsules
Serving: 1 capsule, twice daily
Key ingredients: Dihydroberberine, Alpha Lipoic Acid, GBB, Cinnamon Bark Extract 10:1

Clinically Backed

Supported by research and best practices for wellness.

Fast Absorption

Optimized for quick results and maximum effectiveness.

Daily Support

Easy to include in your routine for consistent benefits.

Safe & Certified

Administered by trained professionals using quality ingredients.

Our Impact in Numbers

2,000+

Happy Clients

10+

Years of Experience

1,200+

IV Therapy and Performance Sessions

98%

Client Satisfaction

What our Customers say

Real experiences from real people who trust us with their care

Hi! Quick update since starting your berberine — my numbers improved a lot.
Total cholesterol dropped 61 points (324 263), and LDL dropped 66 points (233 167) and HDL went up (77 81).
My doctor suggested I double the dose — is that okay to do? Thank you so much!

Sarah M.

Wow!! This!!!! I took the berberine the 2x a day for the 6 months prior to my blood test in October. I wrote to you and told you my cholesterol numbers improved a lot and were in normal range. Your berberine must have helped a lot; along with my diet and exercise! Amazing and fascinating to know!
Proof in the pudding ☺
Thanks! ❤

Jessica T.

🎉🎉 It's Gina !! In Murrieta. I totally want to win the contest 🎉 I've been taking Berberine since November. I lost 25 Pounds. plus food choices and moving more

Gina M.

More importantly, I wanted to let you know that I am obsessed with the NAD product! Initially, I ordered a three month supply and now I'm going to order my second round of a three month supply It's fantastic and I love everything you're doing You ❤
Are ❤
The ❤
Best ❤

Emily K.

Hi Mel I've been using the Nad+ for a couple weeks. I feel incredible. I'm sleeping better. I'm actually having bowel movements every day which never happens and my bladder seems to have calm down. I thought it was my imagination, but it's the supplement. I'm telling everyone I know.!!

Lauren P.

Hey, Mel! I wanted to drop a little note to thank you for the NAD and berberine. I returned from Japan two days ago, and this is the first time in my life that I have so much good energy when returning from a long vacation. I expected to be destroyed by jet lag, but here I am with lots of energy and functioning and sleeping normally. I attribute it to the NAD! And the berberine kept me on track before, during, and after the vacation. Brava to you! XO

Alisha S.

I don’t write many reviews but I’ve been taking this Twelve 28 NAD+ supplement for 5 months and I love this product. I feel like I have more energy throughout the day and can focus more clearly. It’s easy to take and doesn't upset my stomach. It works much better than the well known brand I took previously. It also has 100% recommended daily allowance of biotin, so I no longer have to take a biotin supplement. I’ll definitely keep buying it and highly recommend.

Dougie D.

I love all of nurse Mel’s products! I found her through Jillian! With her berberine I’ve been able to lose weight and maintain it. I also have her protein power!

Beth

The best BERBERINE. I take it twice a day. Cinnamon is a plus. Plus I want to look like the nurse who created it!

Dorothy Lucey

This is an AMAZING product. I got off my statin and this has lowered my cholesterol. I eat good and I work out. The high cholesterol was because of my lineage. I’m 70 years old still working and I love this product 💜💜💜💜

Diane Stockton

The most effective weight management on the market right now. I have been on this for 2 months and I am down 5lbs. I strongly recommend this product along with TWELVE 28 NAD. EXCELLENT SUPPLEMENTS!!!!

Kellie Schnabel

This is a high quality Berberine supplement. It has helped me maintain my body fitness and overall health. I strongly recommend this product.

Gwenn Perez

This is my second purchase of this Muscle and Bone Protein powder. I love the taste! I’ve tried many other protein powders and this is my favorite.

Diane Adams

This Protein Powder is one of the best that I have tried. My bones are stronger, my nails are stronger, I’m retired now and I’m keeping my health in top shape. I put one scoop in my coffee and use a frother to mix it up. This powder is tasteless.

Katherine

I truly love taking my NAD's and have been committed to them for over a year now. I will hope to catch my mailman to ask more questions but more importantly I know I just need to get my NAD replaced so I can continue the benefits from them.
Thank you so, so much.

Alisha Maccoy

I also take @melaniemancil Berberine, Bone Protein Powder and her Nad's. My hair and skin has never looked better. And I'm in my mid sixties. Love her products! P.S. I used to go every 5-6 weeks to get a toner on my hair to cover the grays. Now I go every other month. Thank you Melanie!

Kathy Reed

Hey Mel! I hve to share something with you. I've been sober almost four years and have had food noise and sugar cravings every minute of every day since I stopped drinking, Like crippling some days. And I thought it was something I just had to deal with. I've been taking your berberine for three days and it's gone. GONE! I feel like a new person. So thank you. You are amazing. And so is this product. 💜🌟

Charlotte

Mel, I miss you. I learned so much from you. Your customized approach is so amazing when it comes to GLPI dosage and nutrition advice. Lost 40 lbs because of you and am keeping it off because of all the healthy and satisfying choices you taught me. And you challenged my creativity when it comes to creating meals that are good for me and still taste good. You are the best 🖤

Claudia Stephens

At first I wasn't taking it consistently, honestly because I was not sure what to expect or what the benefits were- I researched a lil and read about it- I started with just one a day- coupled with my nano curcumin- because I was bloated and my lil belly fat just would not go away. Now my bloating is gone and belly fat visibly reduced- my six pack is finally beginning to show- lol- when I get my order I'm bumping up to 2 in the morning- I also carry high cholesterol- always have- my hdl is always higher then my Idl, good ratio- but in my most recent blood test my Idl was lower then my normal- hallelujah.

Betty Taylor

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